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Suppression of autophagy enhances preferential toxicity of paclitaxel to folliculin-deficient renal cancer cells

Overview of attention for article published in Journal of Experimental & Clinical Cancer Research, December 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

blogs
2 blogs
twitter
1 X user

Citations

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40 Dimensions

Readers on

mendeley
27 Mendeley
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Title
Suppression of autophagy enhances preferential toxicity of paclitaxel to folliculin-deficient renal cancer cells
Published in
Journal of Experimental & Clinical Cancer Research, December 2013
DOI 10.1186/1756-9966-32-99
Pubmed ID
Authors

Qi Zhang, Shuhui Si, Sue Schoen, Jindong Chen, Xun-Bo Jin, Guan Wu

Abstract

Paclitaxel, a widely used chemotherapeutic drug, can induce apoptosis in variety of cancer cells. A previous study has shown preferential toxicity of paclitaxel to FLCN-deficient kidney cancer cell line, UOK257. In this report, we investigate the cellular and molecular mechanism of paclitaxel-induced autophagy and apoptosis in renal cancer cells with and without FLCN expression.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 4 15%
Student > Bachelor 4 15%
Student > Ph. D. Student 3 11%
Student > Master 3 11%
Researcher 2 7%
Other 8 30%
Unknown 3 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 52%
Medicine and Dentistry 2 7%
Agricultural and Biological Sciences 2 7%
Nursing and Health Professions 1 4%
Chemistry 1 4%
Other 1 4%
Unknown 6 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2014.
All research outputs
#2,655,094
of 25,373,627 outputs
Outputs from Journal of Experimental & Clinical Cancer Research
#112
of 2,378 outputs
Outputs of similar age
#29,312
of 320,324 outputs
Outputs of similar age from Journal of Experimental & Clinical Cancer Research
#2
of 13 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,378 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,324 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.