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Suppression of autophagy enhances preferential toxicity of paclitaxel to folliculin-deficient renal cancer cells

Overview of attention for article published in Journal of Experimental & Clinical Cancer Research, December 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#3 of 309)
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

blogs
2 blogs
twitter
1 tweeter

Citations

dimensions_citation
29 Dimensions

Readers on

mendeley
26 Mendeley
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Title
Suppression of autophagy enhances preferential toxicity of paclitaxel to folliculin-deficient renal cancer cells
Published in
Journal of Experimental & Clinical Cancer Research, December 2013
DOI 10.1186/1756-9966-32-99
Pubmed ID
Authors

Qi Zhang, Shuhui Si, Sue Schoen, Jindong Chen, Xun-Bo Jin, Guan Wu

Abstract

Paclitaxel, a widely used chemotherapeutic drug, can induce apoptosis in variety of cancer cells. A previous study has shown preferential toxicity of paclitaxel to FLCN-deficient kidney cancer cell line, UOK257. In this report, we investigate the cellular and molecular mechanism of paclitaxel-induced autophagy and apoptosis in renal cancer cells with and without FLCN expression.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 15%
Student > Doctoral Student 3 12%
Student > Master 3 12%
Student > Bachelor 3 12%
Student > Postgraduate 3 12%
Other 7 27%
Unknown 3 12%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 50%
Agricultural and Biological Sciences 4 15%
Medicine and Dentistry 2 8%
Chemistry 1 4%
Engineering 1 4%
Other 0 0%
Unknown 5 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2014.
All research outputs
#364,510
of 5,036,908 outputs
Outputs from Journal of Experimental & Clinical Cancer Research
#3
of 309 outputs
Outputs of similar age
#11,997
of 130,267 outputs
Outputs of similar age from Journal of Experimental & Clinical Cancer Research
#1
of 9 outputs
Altmetric has tracked 5,036,908 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 309 research outputs from this source. They receive a mean Attention Score of 1.6. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 130,267 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them