Title |
Rational design for multifunctional non-liposomal lipid-based nanocarriers for cancer management: theory to practice
|
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Published in |
Journal of Nanobiotechnology, December 2013
|
DOI | 10.1186/1477-3155-11-s1-s6 |
Pubmed ID | |
Authors |
Sabrina Valetti, Simona Mura, Barbara Stella, Patrick Couvreur |
Abstract |
Nanomedicines have gained more and more attention in cancer therapy thanks to their ability to enhance the tumour accumulation and the intracellular uptake of drugs while reducing their inactivation and toxicity. In parallel, nanocarriers have been successfully employed as diagnostic tools increasing imaging resolution holding great promises both in preclinical research and in clinical settings. Lipid-based nanocarriers are a class of biocompatible and biodegradable vehicles that provide advanced delivery of therapeutic and imaging agents, improving pharmacokinetic profile and safety. One of most promising engineering challenges is the design of innovative and versatile multifunctional targeted nanotechnologies for cancer treatment and diagnosis. This review aims to highlight rational approaches to design multifunctional non liposomal lipid-based nanocarriers providing an update of literature in this field. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 2 | 3% |
Switzerland | 1 | 1% |
Unknown | 74 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 19 | 25% |
Researcher | 10 | 13% |
Student > Master | 8 | 10% |
Student > Bachelor | 5 | 6% |
Student > Doctoral Student | 4 | 5% |
Other | 7 | 9% |
Unknown | 24 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 13% |
Biochemistry, Genetics and Molecular Biology | 8 | 10% |
Medicine and Dentistry | 8 | 10% |
Chemistry | 7 | 9% |
Agricultural and Biological Sciences | 6 | 8% |
Other | 11 | 14% |
Unknown | 27 | 35% |