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Spatial distribution of insulin-like growth factor binding protein-2 following hypoxic-ischemic injury

Overview of attention for article published in BMC Neuroscience, December 2013
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Title
Spatial distribution of insulin-like growth factor binding protein-2 following hypoxic-ischemic injury
Published in
BMC Neuroscience, December 2013
DOI 10.1186/1471-2202-14-158
Pubmed ID
Authors

Lauren Fletcher, Elif Isgor, Shane Sprague, Lindsey H Williams, Betty B Alajajian, David F Jimenez, Murat Digicaylioglu

Abstract

Insulin-like growth factor binding protein-2 (IGFBP-2) regulates the bioavailability, transportation, and localization of insulin-like growth factor-I (IGF-I), an effective neuroprotectant in animal stroke models especially when administered intranasally. Therefore, determining IGFBP-2's endogenous distribution in the normal and ischemic brain is essential in maximizing the neuroprotective potential of the intranasal IGF-I treatment approach. However, current data on IGFBP-2 is limited to mRNA and in situ hybridization studies. The purpose of this study was to determine if there are any changes in IGFBP-2 protein levels and distribution in ischemic brain and also to determine if IGFBPs play a role in the transportation of intranasally administered IGF-I into the brain.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 3%
Unknown 35 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 31%
Researcher 7 19%
Student > Bachelor 4 11%
Student > Master 2 6%
Student > Doctoral Student 1 3%
Other 4 11%
Unknown 7 19%
Readers by discipline Count As %
Medicine and Dentistry 12 33%
Neuroscience 8 22%
Agricultural and Biological Sciences 4 11%
Psychology 3 8%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 1 3%
Unknown 7 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 October 2014.
All research outputs
#14,768,891
of 22,736,112 outputs
Outputs from BMC Neuroscience
#654
of 1,241 outputs
Outputs of similar age
#184,405
of 306,115 outputs
Outputs of similar age from BMC Neuroscience
#19
of 34 outputs
Altmetric has tracked 22,736,112 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,241 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,115 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.