Title |
Langerhans cell histiocytosis of the maxillae in a child treated only with chemotherapy: a case report
|
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Published in |
Journal of Medical Case Reports, May 2017
|
DOI | 10.1186/s13256-017-1286-3 |
Pubmed ID | |
Authors |
Angela Pia Cazzolla, Giuseppe Troiano, Khrystyna Zhurakivska, Eugenio Maiorano, Gianfranco Favia, Maria Grazia Lacaita, Giuseppe Marzo, Franca Dicuonzo, Stefano Andresciani, Lorenzo Lo Muzio |
Abstract |
Langerhans cell histiocytosis is a sporadic disease caused by an uncontrolled pathogenic clonal proliferation of dendritic cells that have Langerhans cell characteristics. New treatment protocols provided by the HISTSOC-LCH-III (NCT00276757) trial show an improvement in the survival of children with langerhans cell histiocytosis. We report a case of Langerhans cell histiocytosis, which presented as an osteolytic lesion of the left pre-maxillae enclosing the deciduous incisor and canine in a 7-month-old white Italian boy. He was treated with chemotherapy. He achieved complete remission after 7 months and after 24 months no signs of recurrence were observed. As a result of this treatment, anesthetic sequelae and loss of teeth were avoided; in addition, we prevented a loss of the vertical dimension of occlusion. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Professor | 4 | 17% |
Student > Doctoral Student | 3 | 13% |
Student > Postgraduate | 3 | 13% |
Other | 2 | 8% |
Student > Master | 2 | 8% |
Other | 3 | 13% |
Unknown | 7 | 29% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 13 | 54% |
Nursing and Health Professions | 2 | 8% |
Neuroscience | 1 | 4% |
Engineering | 1 | 4% |
Unknown | 7 | 29% |