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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Anti-inflammatory effects of H2S during acute bacterial infection: a review
|
|---|---|
| Published in |
Journal of Translational Medicine, May 2017
|
| DOI | 10.1186/s12967-017-1206-8 |
| Pubmed ID | |
| Authors |
Francesca Benedetti, Sabrina Curreli, Selvi Krishnan, Sergio Davinelli, Fiorenza Cocchi, Giovanni Scapagnini, Robert C. Gallo, Davide Zella |
| Abstract |
Hydrogen sulfide (H2S), previously only considered a toxic environmental air pollutant, is now increasingly recognized as an important signaling molecule able to modulate several cellular pathways in many human tissues. As demonstrated in recent studies, H2S is produced endogenously in response to different cellular stimuli and plays different roles in controlling a number of physiological responses. The precise role of H2S in inflammation is still largely unknown. In particular, the role of H2S in the regulation of the inflammatory response in acute and chronic infections is being actively investigated because of its potential therapeutic use. To study the effect of H2S as an anti-inflammatory mediator during bacterial infections, we developed an ex vivo model of primary cells and cell lines infected with Mycoplasma. Our data demonstrate a dichotomic effect of H2S on the NF-kB and Nrf-2 molecular pathways, which were inhibited and stimulated, respectively. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 36 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 19% |
| Student > Ph. D. Student | 5 | 14% |
| Student > Doctoral Student | 4 | 11% |
| Student > Master | 4 | 11% |
| Other | 2 | 6% |
| Other | 4 | 11% |
| Unknown | 10 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 7 | 19% |
| Chemistry | 3 | 8% |
| Nursing and Health Professions | 3 | 8% |
| Medicine and Dentistry | 3 | 8% |
| Agricultural and Biological Sciences | 2 | 6% |
| Other | 7 | 19% |
| Unknown | 11 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2017.
All research outputs
#15,459,013
of 22,971,207 outputs
Outputs from Journal of Translational Medicine
#2,251
of 4,014 outputs
Outputs of similar age
#195,195
of 310,780 outputs
Outputs of similar age from Journal of Translational Medicine
#51
of 79 outputs
Altmetric has tracked 22,971,207 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,014 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,780 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.