Title |
A bioinformatic analysis of ribonucleotide reductase genes in phage genomes and metagenomes
|
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Published in |
BMC Ecology and Evolution, February 2013
|
DOI | 10.1186/1471-2148-13-33 |
Pubmed ID | |
Authors |
Bhakti Dwivedi, Bingjie Xue, Daniel Lundin, Robert A Edwards, Mya Breitbart |
Abstract |
Ribonucleotide reductase (RNR), the enzyme responsible for the formation of deoxyribonucleotides from ribonucleotides, is found in all domains of life and many viral genomes. RNRs are also amongst the most abundant genes identified in environmental metagenomes. This study focused on understanding the distribution, diversity, and evolution of RNRs in phages (viruses that infect bacteria). Hidden Markov Model profiles were used to analyze the proteins encoded by 685 completely sequenced double-stranded DNA phages and 22 environmental viral metagenomes to identify RNR homologs in cultured phages and uncultured viral communities, respectively. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 4 | 2% |
Australia | 1 | <1% |
South Africa | 1 | <1% |
Canada | 1 | <1% |
Belgium | 1 | <1% |
Unknown | 159 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 36 | 22% |
Researcher | 30 | 18% |
Student > Bachelor | 18 | 11% |
Student > Master | 17 | 10% |
Student > Doctoral Student | 14 | 8% |
Other | 21 | 13% |
Unknown | 31 | 19% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 23 | 14% |
Immunology and Microbiology | 10 | 6% |
Environmental Science | 9 | 5% |
Chemistry | 4 | 2% |
Other | 13 | 8% |
Unknown | 34 | 20% |