You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Protease inhibitors effectively block cell-to-cell spread of HIV-1 between T cells
|
|---|---|
| Published in |
Retrovirology, December 2013
|
| DOI | 10.1186/1742-4690-10-161 |
| Pubmed ID | |
| Authors |
Boghuma Kabisen Titanji, Marlen Aasa-Chapman, Deenan Pillay, Clare Jolly |
| Abstract |
The Human Immunodeficiency Virus type-1 (HIV-1) spreads by cell-free diffusion and by direct cell-to-cell transfer, the latter being a significantly more efficient mode of transmission. Recently it has been suggested that cell-to-cell spread may permit ongoing virus replication in the presence of antiretroviral therapy (ART) based on studies performed using Reverse Transcriptase Inhibitors (RTIs). Protease Inhibitors (PIs) constitute an important component of ART; however whether this class of inhibitors can suppress cell-to-cell transfer of HIV-1 is unexplored. Here we have evaluated the inhibitory effect of PIs during cell-to-cell spread of HIV-1 between T lymphocytes. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Indonesia | 1 | 1% |
| Ireland | 1 | 1% |
| Canada | 1 | 1% |
| Denmark | 1 | 1% |
| Puerto Rico | 1 | 1% |
| Unknown | 70 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 18 | 24% |
| Student > Ph. D. Student | 12 | 16% |
| Student > Bachelor | 9 | 12% |
| Student > Master | 8 | 11% |
| Student > Doctoral Student | 4 | 5% |
| Other | 12 | 16% |
| Unknown | 12 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 23% |
| Agricultural and Biological Sciences | 14 | 19% |
| Biochemistry, Genetics and Molecular Biology | 11 | 15% |
| Immunology and Microbiology | 7 | 9% |
| Chemistry | 4 | 5% |
| Other | 6 | 8% |
| Unknown | 16 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 March 2014.
All research outputs
#3,457,527
of 24,873,243 outputs
Outputs from Retrovirology
#149
of 1,142 outputs
Outputs of similar age
#39,793
of 319,515 outputs
Outputs of similar age from Retrovirology
#5
of 56 outputs
Altmetric has tracked 24,873,243 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,142 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,515 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.