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Disseminated Bacillus Calmette-Guérin (BCG) infections in infants with immunodeficiency

Overview of attention for article published in BMC Research Notes, May 2017
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Title
Disseminated Bacillus Calmette-Guérin (BCG) infections in infants with immunodeficiency
Published in
BMC Research Notes, May 2017
DOI 10.1186/s13104-017-2499-7
Pubmed ID
Authors

Suleiman Al-Hammadi, Ahmed R. Alsuwaidi, Eman T. Alshamsi, Ghassan A. Ghatasheh, Abdul-Kader Souid

Abstract

The Bacillus Calmette-Guérin (BCG) preparations are live-attenuated derivatives of Mycobacterium bovis. These products are used to vaccinate infants at birth, a practice that may result in a disseminated infection in those patients who have an unidentified immunodeficiency. Patients who were immunized at birth with BCG and who developed a disseminated infection are reported here to emphasize the importance of taking an extensive medical history before ‎giving the BCG vaccine. Patient 1 has a sibling who had familial hemophagocytic lymphohistiocytosis. Patient 2 has a severe immunodeficiency with profound lymphopenia. Patient 3 has a sibling who had a disseminated BCG infection. Patient 4 has two siblings with an immunodeficiency disorder; one sibling passed away in infancy and one is receiving regular immunoglobulin infusions. Patient 5 has profound lymphopenia and his brother had cytomegalovirus (CMV) pneumonitis and passed away in infancy. These unfortunate events could have been avoided by compiling the relevant clinical and laboratory information. These cases also underscore the importance of a strict adherence to the BCG vaccine policies. Local and international registries that estimate the birth prevalence of primary immune deficiencies are needed prior to implementing universal BCG vaccination administration.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 18%
Student > Master 5 13%
Other 4 10%
Researcher 4 10%
Student > Doctoral Student 3 8%
Other 6 15%
Unknown 10 26%
Readers by discipline Count As %
Medicine and Dentistry 12 31%
Biochemistry, Genetics and Molecular Biology 3 8%
Nursing and Health Professions 3 8%
Agricultural and Biological Sciences 3 8%
Veterinary Science and Veterinary Medicine 1 3%
Other 4 10%
Unknown 13 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2017.
All research outputs
#14,034,618
of 15,916,110 outputs
Outputs from BMC Research Notes
#2,878
of 3,486 outputs
Outputs of similar age
#227,996
of 268,535 outputs
Outputs of similar age from BMC Research Notes
#1
of 1 outputs
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So far Altmetric has tracked 3,486 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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