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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Structural predictors of response to intra-articular steroid injection in symptomatic knee osteoarthritis
|
|---|---|
| Published in |
Arthritis Research & Therapy, May 2017
|
| DOI | 10.1186/s13075-017-1292-2 |
| Pubmed ID | |
| Authors |
Nasimah Maricar, Matthew J. Parkes, Michael J. Callaghan, Charles E. Hutchinson, Andrew D. Gait, Richard Hodgson, David T. Felson, Terence W. O’Neill |
| Abstract |
The aim was to examine if structural factors could affect response to intra-articular steroid injections (IASI) in knee osteoarthritis (OA). Persons with painful knee OA participated in an open-label trial of IASI where radiographic joint space narrowing (JSN) and Kellgren-Lawrence (KL) grade, whole-organ magnetic resonance imaging (MRI) scores (WORMS) and quantitative assessment of synovial tissue volume (STV) were assessed on baseline images. Participants completed the Knee Injury and Osteoarthritis Outcome Score (KOOS) and a question about knee pain with a visual analogue scale for pain during nominated activity (VASNA), and Outcome Measures in Rheumatology (OMERACT)-Osteoarthritis Research Society International (OARSI) criteria were used to assess responder status within 2 weeks (short term) and 6 months (longer term). Regression models were used to examine predictors of short and longer term response to IASI. Subjects (n = 207) attended and had IASI. Information on responder status was available on 199 participants. Of these, 188 subjects, mean age 63.2 years (standard deviation (SD) 10.3), 97 (51.6%) female, had x-rays and 120 had MRI scans available. Based on the OMERACT-OARSI criteria, 146 (73.4%) participants responded to therapy and 40 (20.1%) were longer term responders. A few factors were associated with a reduced KOOS-pain and VASNA response though none were associated with OMERACT-OARSI responder status in the short term. Higher MRI meniscal damage (odds ratio (OR) = 0.74; 95% CI 0.55 to 0.98), increasing KL maximal grade (OR = 0.43; 95% CI 0.23 to 0.82) and joint space narrowing (JSN) maximal score (OR = 0.60; 95% CI 0.36 to 0.99) were each associated with a lower odds of longer term responder status. Baseline synovitis was not associated with treatment response. The predicted probability of longer term response decreased from 38% to 12% as baseline maximal JSN increased from grade 0 to 3. Compared with those who have mild structural damage, persons with more severe knee damage on either MRI or x-ray are less likely to respond to knee IASI. ISRCTN.com, ISRCTN07329370 . Registered 21 May 2010. Retrospectively registered. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 30% |
| United States | 2 | 20% |
| Singapore | 1 | 10% |
| Netherlands | 1 | 10% |
| New Zealand | 1 | 10% |
| Australia | 1 | 10% |
| Unknown | 1 | 10% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 70% |
| Practitioners (doctors, other healthcare professionals) | 3 | 30% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 86 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 14 | 16% |
| Student > Postgraduate | 9 | 10% |
| Researcher | 8 | 9% |
| Other | 7 | 8% |
| Professor | 4 | 5% |
| Other | 13 | 15% |
| Unknown | 31 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 28% |
| Nursing and Health Professions | 11 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Psychology | 2 | 2% |
| Business, Management and Accounting | 1 | 1% |
| Other | 8 | 9% |
| Unknown | 37 | 43% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2018.
All research outputs
#2,369,110
of 25,382,440 outputs
Outputs from Arthritis Research & Therapy
#427
of 3,380 outputs
Outputs of similar age
#42,931
of 324,786 outputs
Outputs of similar age from Arthritis Research & Therapy
#8
of 53 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,380 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,786 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.