Title |
The relationship between circulating concentrations of interleukin 17 and C reactive protein in chronic spontaneous urticaria
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Published in |
Allergy, Asthma & Clinical Immunology, May 2017
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DOI | 10.1186/s13223-017-0197-6 |
Pubmed ID | |
Authors |
A. Grzanka, A. Damasiewicz-Bodzek, A. Kasperska-Zajac |
Abstract |
Up-regulation of interleukin 17 (IL-17) family cytokines and acute phase response have been observed in patients with chronic spontaneous urticaria (CSU). It has been demonstrated that IL-17 stimulates C-reactive protein (CRP) expression. To determine relationship between circulating concentrations of IL-17 and CRP in CSU. Concentrations of IL-17 in plasma and CRP in serum were measured in patients with CSU of varying severity and in the healthy subjects. IL-17 and CRP concentrations were significantly higher in CSU patients as compared to the healthy subjects. In addition, there were significant differences in IL-17 and CRP concentrations between CSU patients with mild, moderate-severe symptoms and the healthy subjects. CRP did not correlate significantly with IL-17. Increased circulating IL-17 concentration may represent an independent index of systemic inflammatory response in CSU, which is not related to increased CRP concentration. |
X Demographics
Geographical breakdown
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Mexico | 1 | 33% |
United Kingdom | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 10 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 2 | 20% |
Student > Doctoral Student | 2 | 20% |
Lecturer | 1 | 10% |
Student > Ph. D. Student | 1 | 10% |
Student > Master | 1 | 10% |
Other | 2 | 20% |
Unknown | 1 | 10% |
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Immunology and Microbiology | 1 | 10% |
Other | 0 | 0% |
Unknown | 2 | 20% |