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Diagnostic and treatment modalities for patients with cervical lymph node metastases of unknown primary site – current status and challenges

Overview of attention for article published in Radiation Oncology, May 2017
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Title
Diagnostic and treatment modalities for patients with cervical lymph node metastases of unknown primary site – current status and challenges
Published in
Radiation Oncology, May 2017
DOI 10.1186/s13014-017-0817-9
Pubmed ID
Authors

Jens Müller von der Grün, Aykut Tahtali, Shahram Ghanaati, Claus Rödel, Panagiotis Balermpas

Abstract

This review aims to provide a comprehensive overview of the literature and elucidate open questions for future clinical trials concerning diagnostics and treatment modalities for cervical cancer of unknown primary (CUP). A literature search for head and neck CUP was performed with focus on diagnostics and therapies as well as molecular markers. High level evidence on CUP is limited. However, it seems that a consensus exists regarding the optimal diagnostic procedures. The correct implementation of biomarkers for patient stratification and treatment remains unclear. An even greater dispute dominates about the ideal treatment with publications ranging from sole surgery to surgery with postoperative bilateral radiotherapy with inclusion of the mucosa and concomitant chemotherapy. Cervical CUP represents a very heterogeneous malignant disease. On this account many aspects concerning treatment optimization remain unclear, despite a considerable number of publications in the past. Future research in form of prospective randomized trials is needed in order to better define patient stratification criteria and enable tailored treatment.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 8 15%
Student > Postgraduate 7 13%
Other 7 13%
Researcher 7 13%
Student > Ph. D. Student 4 8%
Other 10 19%
Unknown 9 17%
Readers by discipline Count As %
Medicine and Dentistry 32 62%
Unspecified 2 4%
Nursing and Health Professions 2 4%
Agricultural and Biological Sciences 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 4%
Unknown 12 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 May 2017.
All research outputs
#20,420,242
of 22,971,207 outputs
Outputs from Radiation Oncology
#1,689
of 2,066 outputs
Outputs of similar age
#270,553
of 310,791 outputs
Outputs of similar age from Radiation Oncology
#19
of 28 outputs
Altmetric has tracked 22,971,207 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,066 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,791 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.