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Transcriptome analysis of primary monocytes from HIV-positive patients with differential responses to antiretroviral therapy

Overview of attention for article published in Virology Journal, December 2013
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  • Good Attention Score compared to outputs of the same age (75th percentile)
  • Good Attention Score compared to outputs of the same age and source (67th percentile)

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9 X users

Citations

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17 Dimensions

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39 Mendeley
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Title
Transcriptome analysis of primary monocytes from HIV-positive patients with differential responses to antiretroviral therapy
Published in
Virology Journal, December 2013
DOI 10.1186/1743-422x-10-361
Pubmed ID
Authors

Jing Qin Wu, Tara Ruth Sassé, Monica Miranda Saksena, Nitin K Saksena

Abstract

Despite the significant contributions of monocytes to HIV persistence, the HIV-monocyte interaction remains elusive. For patients on antiretroviral therapy, previous studies observed a virological suppression rate of >70% and suggested complete viral suppression as the primary goal. Although some studies have reported genetic dysregulations associated with HIV disease progression, research on ex vivo-derived monocytic transcriptomes from HIV+ patients with differential responses to therapy is limited. This study investigated the monocytic transcriptome distinctions between patients with sustained virus suppression and those with virological failure during highly active antiretroviral therapy (HAART).

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 38 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 23%
Student > Postgraduate 5 13%
Student > Bachelor 4 10%
Student > Ph. D. Student 4 10%
Student > Master 3 8%
Other 6 15%
Unknown 8 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 28%
Immunology and Microbiology 7 18%
Medicine and Dentistry 6 15%
Biochemistry, Genetics and Molecular Biology 4 10%
Social Sciences 1 3%
Other 0 0%
Unknown 10 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2014.
All research outputs
#7,079,318
of 25,613,746 outputs
Outputs from Virology Journal
#751
of 3,416 outputs
Outputs of similar age
#76,959
of 321,428 outputs
Outputs of similar age from Virology Journal
#19
of 55 outputs
Altmetric has tracked 25,613,746 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 3,416 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.5. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,428 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.