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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Differential therapeutic effects of atomoxetine and methylphenidate in childhood attention deficit/hyperactivity disorder as measured by near-infrared spectroscopy
|
|---|---|
| Published in |
Child and Adolescent Psychiatry and Mental Health, May 2017
|
| DOI | 10.1186/s13034-017-0163-6 |
| Pubmed ID | |
| Authors |
Yoko Nakanishi, Toyosaku Ota, Junzo Iida, Kazuhiko Yamamuro, Naoko Kishimoto, Kosuke Okazaki, Toshifumi Kishimoto |
| Abstract |
The stimulant methylphenidate (MPH) and the nonstimulant atomoxetine (ATX) are the most commonly-prescribed pharmacological treatments for attention deficit/hyperactivity disorder (ADHD). However, the drug-specific mechanism of action on brain function in ADHD patients is not well known. This study examined differences in prefrontal hemodynamic activity between MPH and ATX in children with ADHD as measured by near-infrared spectroscopy (NIRS) using the Stroop color-word task. Thirty children with ADHD participated in the present study. We used 24-channel NIRS (ETG-4000) to measure the relative concentrations of oxyhemoglobin in the frontal lobes of participants in the drug-naïve condition and those who had received MPH (n = 16) or ATX (n = 14) for 12 weeks. Measurements were conducted every 0.1 s during the Stroop color-word task. We used the ADHD RS-IV-J (Home Version) to evaluate ADHD symptoms. Treatment with either MPH or ATX significantly reduced ADHD symptoms, as measured by the ADHD RS-IV-J, and improved performance on the Stroop color-word task in terms of number of correct words. We found significantly higher levels of oxyhemoglobin changes in the prefrontal cortex of participants in the ATX condition compared with the values seen at baseline (pre-ATX). In contrast, we found no oxyhemoglobin changes between pre- and post-treatment with MPH. The present study suggests that MPH and ATX have differential effects on prefrontal hemodynamic activity in children with ADHD. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 82 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 34 | 41% |
| Student > Ph. D. Student | 9 | 11% |
| Researcher | 4 | 5% |
| Student > Doctoral Student | 3 | 4% |
| Professor | 3 | 4% |
| Other | 10 | 12% |
| Unknown | 19 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 39 | 48% |
| Medicine and Dentistry | 6 | 7% |
| Neuroscience | 5 | 6% |
| Biochemistry, Genetics and Molecular Biology | 2 | 2% |
| Linguistics | 1 | 1% |
| Other | 7 | 9% |
| Unknown | 22 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 February 2024.
All research outputs
#16,137,211
of 25,507,011 outputs
Outputs from Child and Adolescent Psychiatry and Mental Health
#541
of 785 outputs
Outputs of similar age
#185,414
of 324,930 outputs
Outputs of similar age from Child and Adolescent Psychiatry and Mental Health
#5
of 13 outputs
Altmetric has tracked 25,507,011 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 785 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.1. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,930 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.