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Experimental tumor growth of canine osteosarcoma cell line on chick embryo chorioallantoic membrane (in vivo studies)

Overview of attention for article published in Acta Veterinaria Scandinavica, May 2017
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Title
Experimental tumor growth of canine osteosarcoma cell line on chick embryo chorioallantoic membrane (in vivo studies)
Published in
Acta Veterinaria Scandinavica, May 2017
DOI 10.1186/s13028-017-0298-8
Pubmed ID
Authors

Magdalena Walewska, Izabella Dolka, Anna Małek, Anna Wojtalewicz, Agata Wojtkowska, Artur Żbikowski, Roman Lechowski, Katarzyna Zabielska-Koczywąs

Abstract

The chick embryo chorioallantoic membrane (CAM) model is extensively used in human medicine in preclinical oncological studies. The CAM model has several advantages: low cost, simple experimental approach, time saving and following "3R principles". Research has shown that the human osteosarcoma cell lines U2OS, MMNG-HOS, and SAOS can form tumors on the CAM. In veterinary medicine, this has been described only for feline fibrosarcomas, feline mammary carcinomas and canine osteosarcomas. However, in case of canine osteosarcomas, it has been shown that only non-adherent osteosarcoma stem cells isolated from KTOSA5 and CSKOS cell lines have the ability to form microtumors on the CAM after an incubation period of 5 days, in contrast to adherent KTOSA5 and CSKOS cells. In the presented study, we have proven that the commercial adherent canine osteosarcoma cell line (D-17) can form vascularized tumors on the CAM after the incubation period of 10 days.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 14%
Student > Ph. D. Student 3 14%
Professor > Associate Professor 2 10%
Student > Master 2 10%
Other 1 5%
Other 2 10%
Unknown 8 38%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 24%
Veterinary Science and Veterinary Medicine 3 14%
Medicine and Dentistry 2 10%
Unspecified 1 5%
Social Sciences 1 5%
Other 1 5%
Unknown 8 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 May 2017.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from Acta Veterinaria Scandinavica
#692
of 837 outputs
Outputs of similar age
#284,274
of 324,616 outputs
Outputs of similar age from Acta Veterinaria Scandinavica
#13
of 14 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 837 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,616 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.