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Impact of 8-week linoleic acid intake in soy oil on Lp-PLA2 activity in healthy adults

Overview of attention for article published in Nutrition & Metabolism, May 2017
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  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

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122 X users
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3 YouTube creators

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Title
Impact of 8-week linoleic acid intake in soy oil on Lp-PLA2 activity in healthy adults
Published in
Nutrition & Metabolism, May 2017
DOI 10.1186/s12986-017-0186-2
Pubmed ID
Authors

Minkyung Kim, Minjoo Kim, Ayoung Lee, Hye Jin Yoo, Jung Soo Her, Sun Ha Jee, Jong Ho Lee

Abstract

No intervention follow-up study has examined the association between plasma n-6 polyunsaturated fatty acids (PUFAs) and lipoprotein-associated phospholipase A2 (Lp-PLA2), which is a risk factor for cardiovascular disease (CVD). We aimed to determine whether the administration of linoleic acid (LA, 18:2n-6) in soy oil affected Lp-PLA2 activity in healthy adults. Self-reported healthy participants (n = 150) were randomly assigned to three groups: a low LA group, in which 10 mL soy oil was replaced with one apple; a medium LA group, in which the typical food intake was maintained; and a high LA group, in which 1/3 cup of cooked refined rice was replaced with 9.9 g of soy oil capsules daily. Plasma fatty acids and Lp-PLA2 activity were measured along with other CVD risk factors. After 8 weeks of treatment, plasma LA levels decreased in the low LA group and increased in the high LA group. The high LA group showed greater increases in apolipoprotein B (apoB) and oxidized low-density lipoprotein (ox-LDL) than those in the low LA group. Plasma LA levels and Lp-PLA2 activities demonstrated greater increases in the high LA group than those in the medium and low LA groups. Changes in plasma LA positively and independently correlated with changes in Lp-PLA2 activity, which was negatively correlated with changes in collagen-epinephrine closure time (CEPI-CT). An increase in plasma LA following intake of soy oil was independently associated with Lp-PLA2 activity, which was also related to apoB, ox-LDL and CEPI-CT. ClinicalTrail.gov Identifier: NCT02753907, registered 25 April 2016 (retrospectively registered).

X Demographics

X Demographics

The data shown below were collected from the profiles of 122 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 43 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 19%
Researcher 7 16%
Student > Master 5 12%
Other 3 7%
Student > Ph. D. Student 3 7%
Other 3 7%
Unknown 14 33%
Readers by discipline Count As %
Medicine and Dentistry 8 19%
Biochemistry, Genetics and Molecular Biology 6 14%
Nursing and Health Professions 5 12%
Agricultural and Biological Sciences 2 5%
Sports and Recreations 1 2%
Other 3 7%
Unknown 18 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 85. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2024.
All research outputs
#514,742
of 25,826,146 outputs
Outputs from Nutrition & Metabolism
#89
of 1,025 outputs
Outputs of similar age
#10,457
of 325,941 outputs
Outputs of similar age from Nutrition & Metabolism
#1
of 7 outputs
Altmetric has tracked 25,826,146 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,025 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.1. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,941 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them