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X Demographics
Mendeley readers
| Title |
Effect of periodontal treatment on the clinical parameters of patients with rheumatoid arthritis: study protocol of the randomized, controlled ESPERA trial
|
|---|---|
| Published in |
Trials, August 2013
|
| DOI | 10.1186/1745-6215-14-253 |
| Pubmed ID | |
| Authors |
Paul Monsarrat, Jean-Noël Vergnes, Alain Cantagrel, Nadège Algans, Sarah Cousty, Philippe Kémoun, Caroline Bertrand, Elise Arrivé, Christophe Bou, Cyril Sédarat, Thierry Schaeverbeke, Cathy Nabet, Michel Sixou |
| Abstract |
Rheumatoid arthritis (RA) is a chronic inflammatory disorder that leads to joint damage, deformity, and pain. It affects approximately 1% of adults in developed countries. Periodontitis is a chronic oral infection, caused by inflammatory reactions to gram-negative anaerobic bacteria, and affecting about 35 to 50% of adults. If left untreated, periodontitis can lead to tooth loss. A significant association has been shown to exist between periodontitis and RA in observational studies. Some intervention studies have suggested that periodontal treatment can reduce serum inflammatory biomarkers such as C-reactive protein, or erythrocyte sedimentation rate. We hypothesize that periodontitis could be an aggravating factor in patients with RA, and that its treatment would improve RA outcomes. The aim of this clinical trial is to assess the effect of periodontal treatment on the biological and clinical parameters of patients with RA. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 197 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Australia | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 194 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 30 | 15% |
| Student > Bachelor | 30 | 15% |
| Student > Postgraduate | 17 | 9% |
| Researcher | 15 | 8% |
| Student > Ph. D. Student | 15 | 8% |
| Other | 34 | 17% |
| Unknown | 56 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 104 | 53% |
| Biochemistry, Genetics and Molecular Biology | 7 | 4% |
| Agricultural and Biological Sciences | 6 | 3% |
| Immunology and Microbiology | 3 | 2% |
| Nursing and Health Professions | 3 | 2% |
| Other | 18 | 9% |
| Unknown | 56 | 28% |