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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase
|
|---|---|
| Published in |
Molecular Neurodegeneration, January 2014
|
| DOI | 10.1186/1750-1326-9-1 |
| Pubmed ID | |
| Authors |
Virginie Buggia-Prévot, Celia G Fernandez, Sean Riordan, Kulandaivelu S Vetrivel, Jelita Roseman, Jack Waters, Vytautas P Bindokas, Robert Vassar, Gopal Thinakaran |
| Abstract |
BACE1 is one of the two enzymes that cleave amyloid precursor protein to generate Alzheimer's disease (AD) beta amyloid peptides. It is widely believed that BACE1 initiates APP processing in endosomes, and in the brain this cleavage is known to occur during axonal transport of APP. In addition, BACE1 accumulates in dystrophic neurites surrounding brain senile plaques in individuals with AD, suggesting that abnormal accumulation of BACE1 at presynaptic terminals contributes to pathogenesis in AD. However, only limited information is available on BACE1 axonal transport and targeting. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 42% |
| United Kingdom | 4 | 33% |
| France | 1 | 8% |
| Unknown | 2 | 17% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 75% |
| Scientists | 2 | 17% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 1% |
| Canada | 1 | 1% |
| Unknown | 97 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 29 | 29% |
| Researcher | 23 | 23% |
| Student > Master | 11 | 11% |
| Student > Doctoral Student | 7 | 7% |
| Student > Bachelor | 7 | 7% |
| Other | 8 | 8% |
| Unknown | 14 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 35 | 35% |
| Neuroscience | 24 | 24% |
| Biochemistry, Genetics and Molecular Biology | 13 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
| Medicine and Dentistry | 5 | 5% |
| Other | 5 | 5% |
| Unknown | 12 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 March 2017.
All research outputs
#1,969,525
of 24,641,620 outputs
Outputs from Molecular Neurodegeneration
#200
of 925 outputs
Outputs of similar age
#22,488
of 316,388 outputs
Outputs of similar age from Molecular Neurodegeneration
#3
of 20 outputs
Altmetric has tracked 24,641,620 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 925 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.9. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,388 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.