You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
| Title |
Extracellular Signals and Pancreatic β-cell Development: A Brief Review
|
|---|---|
| Published in |
Molecular Medicine, December 2002
|
| DOI | 10.1007/bf03402081 |
| Pubmed ID | |
| Authors |
Fang-Xu Jiang, Leonard C. Harrison |
| Abstract |
Cell lineage development is a finely tuned process of proliferation and differentiation, survival and apoptosis, that is regulated by numerous extracellular signals. Here we review some of the extracellular signals--including insoluble cell-cell and extracellular matrix-cell interactions, as well as soluble factors--that appear critical for pancreatic beta-cell development. Knowledge of how these signals control the development of pancreatic endocrine stem/precursor cells into fully functional insulin-secreting beta cells is a platform for the restoration of beta-cell function and the cure therapy of type 1 diabetes. |
Mendeley readers
The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Norway | 1 | 4% |
| Unknown | 23 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 58% |
| Researcher | 3 | 13% |
| Student > Master | 2 | 8% |
| Student > Bachelor | 1 | 4% |
| Student > Doctoral Student | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 2 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 15 | 63% |
| Biochemistry, Genetics and Molecular Biology | 4 | 17% |
| Business, Management and Accounting | 1 | 4% |
| Medicine and Dentistry | 1 | 4% |
| Engineering | 1 | 4% |
| Other | 0 | 0% |
| Unknown | 2 | 8% |