Title |
Autophagy involved in lipopolysaccharide-induced foam cell formation is mediated by adipose differentiation-related protein
|
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Published in |
Lipids in Health and Disease, January 2014
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DOI | 10.1186/1476-511x-13-10 |
Pubmed ID | |
Authors |
Xuyang Feng, Yuan Yuan, Chao Wang, Jun Feng, Zuyi Yuan, Xiumin Zhang, Wen Sui, Peizhen Hu, Pengfei Zheng, Jing Ye |
Abstract |
Autophagy is an essential process for breaking down macromolecules and aged/damaged cellular organelles to maintain cellular energy balance and cellular nutritional status. The idea that autophagy regulates lipid metabolism is an emerging concept with important implications for atherosclerosis. However, the potential role of autophagy and its relationship with lipid metabolism in foam cell formation remains unclear. In this study, we found that autophagy was involved in the lipopolysaccharide (LPS)-induced the formation of foam cells and was at least partially dependent on adipose differentiation-related protein (ADRP). |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Russia | 1 | 3% |
Unknown | 30 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 6 | 19% |
Student > Master | 6 | 19% |
Researcher | 4 | 13% |
Student > Bachelor | 3 | 10% |
Student > Doctoral Student | 2 | 6% |
Other | 5 | 16% |
Unknown | 5 | 16% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 9 | 29% |
Agricultural and Biological Sciences | 9 | 29% |
Medicine and Dentistry | 3 | 10% |
Psychology | 2 | 6% |
Unspecified | 1 | 3% |
Other | 1 | 3% |
Unknown | 6 | 19% |