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Subclinical Hypothyroidism in Children: Normal Variation or Sign of a Failing Thyroid Gland?

Overview of attention for article published in International Journal of Pediatric Endocrinology, May 2010
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Title
Subclinical Hypothyroidism in Children: Normal Variation or Sign of a Failing Thyroid Gland?
Published in
International Journal of Pediatric Endocrinology, May 2010
DOI 10.1155/2010/281453
Pubmed ID
Authors

Paul B. Kaplowitz

Abstract

Subclinical hypothyroidism (SCH), defined by a normal total or free T4 level and a mildly elevated TSH (typically 5-10 mU/L), is common in children, but there is currently no consensus on management. Several recent pediatric studies indicate that progression of SCH to overt hypothyroidism (OH) is uncommon and that over a period of several years, elevated TSH usually either normalizes or persists but does not increase. The etiology appears to be multifactorial, with some cases representing minor developmental abnormalities, some related to obesity, some to mild autoimmune thyroiditis, and some associated with mutations in the gene for the TSH-receptor. There are no pediatric studies showing clinical benefit of treating these children with thyroid hormone, but additional studies in this area are needed. Since few cases of pediatric SCH progress to OH, treatment can be deferred, and periodic follow-up testing may be the preferred strategy, with elevated thyroid antibodies or a goiter being considered risk factors for eventual OH.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 1%
Denmark 1 1%
Romania 1 1%
Unknown 80 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 14%
Student > Postgraduate 12 14%
Student > Bachelor 9 11%
Other 8 10%
Researcher 8 10%
Other 19 23%
Unknown 15 18%
Readers by discipline Count As %
Medicine and Dentistry 49 59%
Agricultural and Biological Sciences 6 7%
Nursing and Health Professions 5 6%
Psychology 2 2%
Biochemistry, Genetics and Molecular Biology 1 1%
Other 5 6%
Unknown 15 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 January 2014.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from International Journal of Pediatric Endocrinology
#128
of 137 outputs
Outputs of similar age
#99,201
of 103,776 outputs
Outputs of similar age from International Journal of Pediatric Endocrinology
#7
of 8 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 137 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 103,776 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one.