Title |
Synovial membrane protein expression differs between juvenile idiopathic arthritis subtypes in early disease
|
---|---|
Published in |
Arthritis Research & Therapy, January 2014
|
DOI | 10.1186/ar4434 |
Pubmed ID | |
Authors |
Sorcha Finnegan, Joanne Robson, Caitriona Scaife, Catherine McAllister, Stephen R Pennington, David S Gibson, Madeleine E Rooney |
Abstract |
Juvenile idiopathic arthritis (JIA) is the most common rheumatological disease of childhood with a prevalence of around 1 in 1000. Without appropriate treatment it can have devastating consequences including permanent disability from joint destruction and growth deformities. Disease aetiology remains unknown. Investigation of disease pathology at the level of the synovial membrane is required if we want to begin to understand the disease at the molecular and biochemical level. The synovial membrane proteome from early disease-stage, treatment naive JIA patients was compared between polyarticular and oligoarticular subgroups. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Canada | 1 | 3% |
Unknown | 34 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 7 | 20% |
Student > Master | 5 | 14% |
Student > Bachelor | 5 | 14% |
Researcher | 4 | 11% |
Other | 3 | 9% |
Other | 6 | 17% |
Unknown | 5 | 14% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 14 | 40% |
Agricultural and Biological Sciences | 5 | 14% |
Biochemistry, Genetics and Molecular Biology | 4 | 11% |
Mathematics | 2 | 6% |
Engineering | 2 | 6% |
Other | 3 | 9% |
Unknown | 5 | 14% |