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Mendeley readers
| Title |
Closing gaps in the human genome using sequencing by synthesis
|
|---|---|
| Published in |
Genome Biology, June 2009
|
| DOI | 10.1186/gb-2009-10-6-r60 |
| Pubmed ID | |
| Authors |
Manuel Garber, Michael C Zody, Harindra M Arachchi, Aaron Berlin, Sante Gnerre, Lisa M Green, Niall Lennon, Chad Nusbaum |
| Abstract |
The most recent release of the finished human genome contains 260 euchromatic gaps (excluding chromosome Y). Recent work has helped explain a large number of these unresolved regions as 'structural' in nature. Another class of gaps is likely to be refractory to clone-based approaches, and cannot be approached in ways previously described. We present an approach for closing these gaps using 454 sequencing. As a proof of principle, we closed all three remaining non-structural gaps in chromosome 15. |
Mendeley readers
The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 4 | 4% |
| United States | 3 | 3% |
| Italy | 1 | <1% |
| South Africa | 1 | <1% |
| China | 1 | <1% |
| United Kingdom | 1 | <1% |
| Russia | 1 | <1% |
| Philippines | 1 | <1% |
| Unknown | 89 | 87% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 33 | 32% |
| Student > Ph. D. Student | 23 | 23% |
| Professor | 9 | 9% |
| Professor > Associate Professor | 8 | 8% |
| Student > Bachelor | 6 | 6% |
| Other | 14 | 14% |
| Unknown | 9 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 64 | 63% |
| Biochemistry, Genetics and Molecular Biology | 14 | 14% |
| Computer Science | 3 | 3% |
| Medicine and Dentistry | 3 | 3% |
| Immunology and Microbiology | 2 | 2% |
| Other | 4 | 4% |
| Unknown | 12 | 12% |