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Validated method to measure yakuchinone A in plasma by LC-MS/MS and its application to a pharmacokinetic study in rats

Overview of attention for article published in BMC Chemistry, January 2014
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Title
Validated method to measure yakuchinone A in plasma by LC-MS/MS and its application to a pharmacokinetic study in rats
Published in
BMC Chemistry, January 2014
DOI 10.1186/1752-153x-8-2
Pubmed ID
Authors

Feng Chen, Hai-Long Li, Yin-Feng Tan, Wei-Wei Guan, Yong-Hui Li, Jun-Qing Zhang

Abstract

Yakuchinone A has a plethora of beneficial biological effects. However, the pharmacokinetic (PK) data of yakuchinone A still remain unknown so far. Furthermore, the quantification of yakuchinone A in biological samples has not been reported in the literature. Therefore, in the present study we aimed to develop a new method for the fast, efficient and accurate assessment of yakuchinone A concentration in plasma, as a means for facilitating the PK evaluation of yakuchinone A.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 1 13%
Student > Ph. D. Student 1 13%
Professor > Associate Professor 1 13%
Student > Bachelor 1 13%
Student > Master 1 13%
Other 0 0%
Unknown 3 38%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 2 25%
Chemistry 2 25%
Agricultural and Biological Sciences 1 13%
Unspecified 1 13%
Unknown 2 25%