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Mendeley readers
Attention Score in Context
| Title |
Tolerability and efficacy of a combination of paracetamol and caffeine in the treatment of tension-type headache: a randomised, double-blind, double-dummy, cross-over study versus placebo and naproxen sodium
|
|---|---|
| Published in |
The Journal of Headache and Pain, September 2008
|
| DOI | 10.1007/s10194-008-0071-5 |
| Pubmed ID | |
| Authors |
Luigi Alberto Pini, Enrico Del Bene, Giorgio Zanchin, Paola Sarchielli, Girolamo Di Trapani, Maria Pia Prudenzano, Giovanni LaPegna, Lidia Savi, Giorgio Di Loreto, Paolo Dionisio, Franco Granella |
| Abstract |
The main aim of this study was to confirm in an Italian population affected by tension-type headache (TTH) the good profile of safety and tolerability of the combination paracetamol 1,000 mg-caffeine 130 mg (PCF) observed in previous studies, by a comparison with naproxen sodium 550 mg (NAP) and placebo (PLA). A secondary objective was to assess the efficacy of PCF in the acute treatment of TTH. This was a multicentre, randomised, double-blind, double-dummy, crossover, placebo-controlled trial. Tolerability was assessed by recording adverse events by the patient in the 4-h post-dose treatment. To assess the efficacy, the sum of pain intensity differences (SPID) and the total pain relief (TOTPAR) were calculated. Comparing PCF and NAP and PCF and PLA for tolerability, the difference was nonsignificant but the result regarding noninferiority was inconclusive, whilst NAP was noninferior to PLA. As regards SPID and TOTPAR, both PCF and NAP were better than placebo (P < 0.05), but not significantly different from each other. In conclusion, PCF was well-tolerated and effective in the treatment of acute TTH. |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 63 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 16% |
| Student > Bachelor | 10 | 16% |
| Student > Master | 7 | 11% |
| Other | 6 | 9% |
| Student > Postgraduate | 5 | 8% |
| Other | 15 | 23% |
| Unknown | 11 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 32 | 50% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 11% |
| Environmental Science | 2 | 3% |
| Nursing and Health Professions | 2 | 3% |
| Psychology | 2 | 3% |
| Other | 4 | 6% |
| Unknown | 15 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 July 2013.
All research outputs
#7,866,480
of 23,849,058 outputs
Outputs from The Journal of Headache and Pain
#708
of 1,417 outputs
Outputs of similar age
#32,589
of 89,619 outputs
Outputs of similar age from The Journal of Headache and Pain
#2
of 6 outputs
Altmetric has tracked 23,849,058 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,417 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.6. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 89,619 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.