Title |
A comprehensive microRNA expression profile of the backfat tissue from castrated and intact full-sib pair male pigs
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Published in |
BMC Genomics, January 2014
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DOI | 10.1186/1471-2164-15-47 |
Pubmed ID | |
Authors |
Ying Bai, Jin-Ming Huang, Gang Liu, Ji-Bin Zhang, Jian-Ying Wang, Cheng-Kun Liu, Mei-Ying Fang |
Abstract |
It is widely known that castration has a significant effect on the accumulation of adipose tissue. microRNAs (miRNAs) are known to be involved in fat deposition and to be regulated by the androgen-induced androgen receptor (AR). However, there is little understanding of the relationship between miRNAs and fat deposition after castration. In this study, the high-throughput SOLiD sequencing approach was used to identify and characterize miRNA expression in backfat from intact and castrated full-sib male 23-week-old pigs. The patterns of adipogenesis and fat deposition were compared between castrated and intact male pigs. |
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