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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A role of ADAR2 and RNA editing of glutamate receptors in mood disorders and schizophrenia
|
|---|---|
| Published in |
Molecular Brain, January 2014
|
| DOI | 10.1186/1756-6606-7-5 |
| Pubmed ID | |
| Authors |
Mie Kubota-Sakashita, Kazuya Iwamoto, Miki Bundo, Tadafumi Kato |
| Abstract |
Pre-mRNAs of 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propanoic acid (AMPA)/kainate glutamate receptors undergo post-transcriptional modification known as RNA editing that is mediated by adenosine deaminase acting on RNA type 2 (ADAR2). This modification alters the amino acid sequence and function of the receptor. Glutamatergic signaling has been suggested to have a role in mood disorders and schizophrenia, but it is unknown whether altered RNA editing of AMPA/kainate receptors has pathophysiological significance in these mental disorders. In this study, we found that ADAR2 expression tended to be decreased in the postmortem brains of patients with schizophrenia and bipolar disorder. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| India | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 105 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 18 | 17% |
| Student > Ph. D. Student | 17 | 16% |
| Researcher | 17 | 16% |
| Student > Master | 15 | 14% |
| Other | 6 | 6% |
| Other | 17 | 16% |
| Unknown | 18 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 23 | 21% |
| Agricultural and Biological Sciences | 22 | 20% |
| Medicine and Dentistry | 10 | 9% |
| Neuroscience | 8 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
| Other | 14 | 13% |
| Unknown | 26 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 February 2014.
All research outputs
#15,290,667
of 22,739,983 outputs
Outputs from Molecular Brain
#669
of 1,103 outputs
Outputs of similar age
#188,685
of 305,591 outputs
Outputs of similar age from Molecular Brain
#17
of 28 outputs
Altmetric has tracked 22,739,983 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,103 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,591 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.