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Comparative analysis of the complete genome of KPC-2-producing Klebsiella pneumoniae Kp13 reveals remarkable genome plasticity and a wide repertoire of virulence and resistance mechanisms

Overview of attention for article published in BMC Genomics, January 2014
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Title
Comparative analysis of the complete genome of KPC-2-producing Klebsiella pneumoniae Kp13 reveals remarkable genome plasticity and a wide repertoire of virulence and resistance mechanisms
Published in
BMC Genomics, January 2014
DOI 10.1186/1471-2164-15-54
Pubmed ID
Authors

Pablo Ivan Pereira Ramos, Renata Christina Picão, Luiz Gonzaga Paula de Almeida, Nicholas Costa B Lima, Raquel Girardello, Ana Carolina P Vivan, Danilo E Xavier, Fernando G Barcellos, Marsileni Pelisson, Eliana C Vespero, Claudine Médigue, Ana Tereza Ribeiro de Vasconcelos, Ana Cristina Gales, Marisa Fabiana Nicolás

Abstract

Klebsiella pneumoniae is an important opportunistic pathogen associated with nosocomial and community-acquired infections. A wide repertoire of virulence and antimicrobial resistance genes is present in K. pneumoniae genomes, which can constitute extra challenges in the treatment of infections caused by some strains. K. pneumoniae Kp13 is a multidrug-resistant strain responsible for causing a large nosocomial outbreak in a teaching hospital located in Southern Brazil. Kp13 produces K. pneumoniae carbapenemase (KPC-2) but is unrelated to isolates belonging to ST 258 and ST 11, the main clusters associated with the worldwide dissemination of KPC-producing K. pneumoniae. In this report, we perform a genomic comparison between Kp13 and each of the following three K. pneumoniae genomes: MGH 78578, NTUH-K2044 and 342.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 184 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 5 3%
India 2 1%
Sudan 1 <1%
France 1 <1%
Portugal 1 <1%
Belgium 1 <1%
Denmark 1 <1%
United States 1 <1%
Unknown 171 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 38 21%
Researcher 34 18%
Student > Master 31 17%
Student > Doctoral Student 12 7%
Student > Bachelor 11 6%
Other 26 14%
Unknown 32 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 49 27%
Biochemistry, Genetics and Molecular Biology 32 17%
Medicine and Dentistry 25 14%
Immunology and Microbiology 13 7%
Pharmacology, Toxicology and Pharmaceutical Science 6 3%
Other 12 7%
Unknown 47 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 January 2014.
All research outputs
#20,217,843
of 22,741,406 outputs
Outputs from BMC Genomics
#9,258
of 10,630 outputs
Outputs of similar age
#264,596
of 305,705 outputs
Outputs of similar age from BMC Genomics
#389
of 442 outputs
Altmetric has tracked 22,741,406 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,630 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,705 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 442 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.