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Bioinformatic flowchart and database to investigate the origins and diversity of Clan AA peptidases

Overview of attention for article published in Biology Direct, January 2009
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Title
Bioinformatic flowchart and database to investigate the origins and diversity of Clan AA peptidases
Published in
Biology Direct, January 2009
DOI 10.1186/1745-6150-4-3
Pubmed ID
Authors

Carlos Llorens, Ricardo Futami, Gabriel Renaud, Andrés Moya

Abstract

Clan AA of aspartic peptidases relates the family of pepsin monomers evolutionarily with all dimeric peptidases encoded by eukaryotic LTR retroelements. Recent findings describing various pools of single-domain nonviral host peptidases, in prokaryotes and eukaryotes, indicate that the diversity of clan AA is larger than previously thought. The ensuing approach to investigate this enzyme group is by studying its phylogeny. However, clan AA is a difficult case to study due to the low similarity and different rates of evolution. This work is an ongoing attempt to investigate the different clan AA families to understand the cause of their diversity.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Chile 1 3%
United States 1 3%
Canada 1 3%
Unknown 28 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 31%
Student > Ph. D. Student 5 16%
Student > Master 4 13%
Professor 2 6%
Student > Bachelor 2 6%
Other 7 22%
Unknown 2 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 59%
Medicine and Dentistry 3 9%
Chemistry 2 6%
Computer Science 2 6%
Mathematics 1 3%
Other 3 9%
Unknown 2 6%