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CD44 expression positively correlates with Foxp3 expression and suppressive function of CD4+ Treg cells

Overview of attention for article published in Biology Direct, October 2009
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Title
CD44 expression positively correlates with Foxp3 expression and suppressive function of CD4+ Treg cells
Published in
Biology Direct, October 2009
DOI 10.1186/1745-6150-4-40
Pubmed ID
Authors

Tie Liu, Lynn Soong, Gang Liu, Rolf König, Ashok K Chopra

Abstract

CD4(+)CD25(+) regulatory T (T(reg)) cells develop in the thymus and can suppress T cell proliferation, modulated by Foxp3 and cytokines; however, the relevance of CD44 in T(reg) cell development is less clear. To address this issue, we analyzed Foxp3 expression in CD44(+) T(reg) cells by using multiple parameters, measured the levels of the immunoregulatory cytokine interleukin (IL)-10 in various thymocyte subsets, and determined the suppressor activity in different splenic T(reg) cell populations.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Germany 1 1%
Unknown 86 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 30%
Researcher 14 16%
Student > Doctoral Student 9 10%
Student > Bachelor 9 10%
Student > Master 6 7%
Other 13 15%
Unknown 11 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 29 33%
Medicine and Dentistry 16 18%
Immunology and Microbiology 15 17%
Biochemistry, Genetics and Molecular Biology 12 14%
Computer Science 1 1%
Other 3 3%
Unknown 12 14%