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Mendeley readers
| Title |
Undetected antisense tRNAs in mitochondrial genomes?
|
|---|---|
| Published in |
Biology Direct, June 2010
|
| DOI | 10.1186/1745-6150-5-39 |
| Pubmed ID | |
| Authors |
Hervé Seligmann |
| Abstract |
The hypothesis that both mitochondrial (mt) complementary DNA strands of tRNA genes code for tRNAs (sense-antisense coding) is explored. This could explain why mt tRNA mutations are 6.5 times more frequently pathogenic than in other mt sequences. Antisense tRNA expression is plausible because tRNA punctuation signals mt sense RNA maturation: both sense and antisense tRNAs form secondary structures potentially signalling processing. Sense RNA maturation processes by default 11 antisense tRNAs neighbouring sense genes. If antisense tRNAs are expressed, processed antisense tRNAs should have adapted more for translational activity than unprocessed ones. Four tRNA properties are examined: antisense tRNA 5' and 3' end processing by sense RNA maturation and its accuracy, cloverleaf stability and misacylation potential. |
Mendeley readers
The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 1 | 4% |
| Greece | 1 | 4% |
| Germany | 1 | 4% |
| Unknown | 21 | 88% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 38% |
| Professor > Associate Professor | 4 | 17% |
| Student > Ph. D. Student | 2 | 8% |
| Student > Doctoral Student | 2 | 8% |
| Student > Master | 2 | 8% |
| Other | 1 | 4% |
| Unknown | 4 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 12 | 50% |
| Biochemistry, Genetics and Molecular Biology | 3 | 13% |
| Veterinary Science and Veterinary Medicine | 1 | 4% |
| Mathematics | 1 | 4% |
| Physics and Astronomy | 1 | 4% |
| Other | 2 | 8% |
| Unknown | 4 | 17% |