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Genetic characterization of Hawaiian isolates of Plasmodium relictumreveals mixed-genotype infections

Overview of attention for article published in Biology Direct, June 2008
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Title
Genetic characterization of Hawaiian isolates of Plasmodium relictumreveals mixed-genotype infections
Published in
Biology Direct, June 2008
DOI 10.1186/1745-6150-3-25
Pubmed ID
Authors

Susan I Jarvi, Margaret EM Farias, Carter T Atkinson

Abstract

The relatively recent introduction of a highly efficient mosquito vector and an avian pathogen (Plasmodium relictum) to an isolated island ecosystem with naïve, highly susceptible avian hosts provides a unique opportunity to investigate evolution of virulence in a natural system. Mixed infections can significantly contribute to the uncertainty in host-pathogen dynamics with direct impacts on virulence. Toward further understanding of how host-parasite and parasite-parasite relationships may impact virulence, this study characterizes within-host diversity of malaria parasite populations based on genetic analysis of the trap (thrombospondin-related anonymous protein) gene in isolates originating from Hawaii, Maui and Kauai Islands.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 3%
Lithuania 2 2%
United Kingdom 2 2%
Canada 1 1%
Colombia 1 1%
Unknown 84 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 22 24%
Student > Ph. D. Student 15 16%
Student > Master 15 16%
Student > Bachelor 9 10%
Student > Doctoral Student 6 6%
Other 16 17%
Unknown 10 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 57 61%
Environmental Science 7 8%
Biochemistry, Genetics and Molecular Biology 5 5%
Immunology and Microbiology 4 4%
Medicine and Dentistry 3 3%
Other 6 6%
Unknown 11 12%