Title |
Genetic characterization of Hawaiian isolates of Plasmodium relictumreveals mixed-genotype infections
|
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Published in |
Biology Direct, June 2008
|
DOI | 10.1186/1745-6150-3-25 |
Pubmed ID | |
Authors |
Susan I Jarvi, Margaret EM Farias, Carter T Atkinson |
Abstract |
The relatively recent introduction of a highly efficient mosquito vector and an avian pathogen (Plasmodium relictum) to an isolated island ecosystem with naïve, highly susceptible avian hosts provides a unique opportunity to investigate evolution of virulence in a natural system. Mixed infections can significantly contribute to the uncertainty in host-pathogen dynamics with direct impacts on virulence. Toward further understanding of how host-parasite and parasite-parasite relationships may impact virulence, this study characterizes within-host diversity of malaria parasite populations based on genetic analysis of the trap (thrombospondin-related anonymous protein) gene in isolates originating from Hawaii, Maui and Kauai Islands. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 3 | 3% |
Lithuania | 2 | 2% |
United Kingdom | 2 | 2% |
Canada | 1 | 1% |
Colombia | 1 | 1% |
Unknown | 84 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 22 | 24% |
Student > Ph. D. Student | 15 | 16% |
Student > Master | 15 | 16% |
Student > Bachelor | 9 | 10% |
Student > Doctoral Student | 6 | 6% |
Other | 16 | 17% |
Unknown | 10 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 57 | 61% |
Environmental Science | 7 | 8% |
Biochemistry, Genetics and Molecular Biology | 5 | 5% |
Immunology and Microbiology | 4 | 4% |
Medicine and Dentistry | 3 | 3% |
Other | 6 | 6% |
Unknown | 11 | 12% |