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FOXP3 and GARP (LRRC32): the master and its minion

Overview of attention for article published in Biology Direct, February 2010
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Title
FOXP3 and GARP (LRRC32): the master and its minion
Published in
Biology Direct, February 2010
DOI 10.1186/1745-6150-5-8
Pubmed ID
Authors

Michael Probst-Kepper, Jan Buer

Abstract

The transcription factor FOXP3 is essential for the development and function of CD4+CD25hiFOXP3+ regulatory T (T(reg)) cells, but also expressed in activated human helper T cells without acquisition of a regulatory phenotype. This comment focuses on glycoprotein-A repetitions predominant (GARP or LRRC32) recently identified as specific marker of activated human T(reg) cells, which may provide the missing link toward a better molecular definition of the regulatory phenotype.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 3%
Chile 1 1%
Canada 1 1%
China 1 1%
Korea, Republic of 1 1%
United States 1 1%
Unknown 86 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 33%
Researcher 26 28%
Student > Master 7 7%
Other 6 6%
Student > Doctoral Student 4 4%
Other 14 15%
Unknown 6 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 43 46%
Medicine and Dentistry 17 18%
Immunology and Microbiology 12 13%
Biochemistry, Genetics and Molecular Biology 7 7%
Unspecified 2 2%
Other 5 5%
Unknown 8 9%