You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
| Title |
The stochastic behavior of a molecular switching circuit with feedback
|
|---|---|
| Published in |
Biology Direct, May 2007
|
| DOI | 10.1186/1745-6150-2-13 |
| Pubmed ID | |
| Authors |
Supriya Krishnamurthy, Eric Smith, David Krakauer, Walter Fontana |
| Abstract |
Using a statistical physics approach, we study the stochastic switching behavior of a model circuit of multisite phosphorylation and dephosphorylation with feedback. The circuit consists of a kinase and phosphatase acting on multiple sites of a substrate that, contingent on its modification state, catalyzes its own phosphorylation and, in a symmetric scenario, dephosphorylation. The symmetric case is viewed as a cartoon of conflicting feedback that could result from antagonistic pathways impinging on the state of a shared component. |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| France | 1 | 2% |
| Sweden | 1 | 2% |
| Portugal | 1 | 2% |
| Canada | 1 | 2% |
| United Kingdom | 1 | 2% |
| Japan | 1 | 2% |
| Serbia | 1 | 2% |
| Unknown | 50 | 85% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 27% |
| Researcher | 14 | 24% |
| Student > Bachelor | 6 | 10% |
| Professor > Associate Professor | 6 | 10% |
| Student > Master | 6 | 10% |
| Other | 8 | 14% |
| Unknown | 3 | 5% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 42% |
| Physics and Astronomy | 8 | 14% |
| Biochemistry, Genetics and Molecular Biology | 6 | 10% |
| Computer Science | 4 | 7% |
| Mathematics | 2 | 3% |
| Other | 11 | 19% |
| Unknown | 3 | 5% |