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Bayesian classification of residues associated with protein functional divergence: Arf and Arf-like GTPases

Overview of attention for article published in Biology Direct, December 2010
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Title
Bayesian classification of residues associated with protein functional divergence: Arf and Arf-like GTPases
Published in
Biology Direct, December 2010
DOI 10.1186/1745-6150-5-66
Pubmed ID
Authors

Andrew F Neuwald

Abstract

Certain residues within proteins are highly conserved across very distantly related organisms, yet their (presumably critical) structural or mechanistic roles are completely unknown. To obtain clues regarding such residues within Arf and Arf-like (Arf/Arl) GTPases--which function as on/off switches regulating vesicle trafficking, phospholipid metabolism and cytoskeletal remodeling--I apply a new sampling procedure for comparative sequence analysis, termed multiple category Bayesian Partitioning with Pattern Selection (mcBPPS).

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Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 11%
United Kingdom 1 5%
Unknown 16 84%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 37%
Student > Master 3 16%
Professor 2 11%
Professor > Associate Professor 2 11%
Lecturer > Senior Lecturer 1 5%
Other 3 16%
Unknown 1 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 47%
Biochemistry, Genetics and Molecular Biology 4 21%
Sports and Recreations 1 5%
Social Sciences 1 5%
Medicine and Dentistry 1 5%
Other 1 5%
Unknown 2 11%