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Epigenetic hereditary transcription profiles II, aging revisited

Overview of attention for article published in Biology Direct, December 2007
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Title
Epigenetic hereditary transcription profiles II, aging revisited
Published in
Biology Direct, December 2007
DOI 10.1186/1745-6150-2-39
Pubmed ID
Authors

Johannes WIM Simons

Abstract

Previously, we have shown that deviations from the average transcription profile of a group of functionally related genes can be epigenetically transmitted to daughter cells, thereby implicating nuclear programming as the cause. As a first step in further characterizing this phenomenon it was necessary to determine to what extent such deviations occur in non-tumorigenic tissues derived from normal individuals. To this end, a microarray database derived from 90 human donors aged between 22 to 87 years was used to study deviations from the average transcription profile of the proteasome genes.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 27%
Professor > Associate Professor 2 18%
Lecturer 1 9%
Student > Doctoral Student 1 9%
Student > Ph. D. Student 1 9%
Other 3 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 73%
Biochemistry, Genetics and Molecular Biology 2 18%
Medicine and Dentistry 1 9%