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MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

Overview of attention for article published in Biology Direct, May 2011
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Title
MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival
Published in
Biology Direct, May 2011
DOI 10.1186/1745-6150-6-23
Pubmed ID
Authors

Jianxiang Chi, Erica Ballabio, Xiao-He Chen, Rajko Kušec, Steve Taylor, Deborah Hay, Daniela Tramonti, Nigel J Saunders, Timothy Littlewood, Francesco Pezzella, Jacqueline Boultwood, James S Wainscoat, Christian SR Hatton, Charles H Lawrie

Abstract

MicroRNAs are small RNA species that regulate gene expression post-transcriptionally and are aberrantly expressed in many cancers including hematological malignancies. However, the role of microRNAs in the pathogenesis of multiple myeloma (MM) is only poorly understood. We therefore used microarray analysis to elucidate the complete miRNome (miRBase version 13.0) of purified tumor (CD138+) cells from 33 patients with MM, 5 patients with monoclonal gammopathy of undetermined significance (MGUS) and 9 controls.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Denmark 1 1%
Czechia 1 1%
Unknown 87 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 25 28%
Student > Ph. D. Student 16 18%
Student > Master 14 16%
Student > Bachelor 6 7%
Other 6 7%
Other 17 19%
Unknown 6 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 35 39%
Medicine and Dentistry 27 30%
Biochemistry, Genetics and Molecular Biology 12 13%
Environmental Science 3 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 1%
Other 5 6%
Unknown 7 8%