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Mendeley readers
| Title |
The archaeo-eukaryotic GINS proteins and the archaeal primase catalytic subunit PriS share a common domain
|
|---|---|
| Published in |
Biology Direct, April 2010
|
| DOI | 10.1186/1745-6150-5-17 |
| Pubmed ID | |
| Authors |
Agnieszka Swiatek, Stuart A MacNeill |
| Abstract |
Primase and GINS are essential factors for chromosomal DNA replication in eukaryotic and archaeal cells. Here we describe a previously undetected relationship between the C-terminal domain of the catalytic subunit (PriS) of archaeal primase and the B-domains of the archaeo-eukaryotic GINS proteins in the form of a conserved structural domain comprising a three-stranded antiparallel beta-sheet adjacent to an alpha-helix and a two-stranded beta-sheet or hairpin. The presence of a shared domain in archaeal PriS and GINS proteins, the genes for which are often found adjacent on the chromosome, suggests simple mechanisms for the evolution of these proteins. |
Mendeley readers
The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 34 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 12 | 35% |
| Student > Ph. D. Student | 7 | 21% |
| Student > Master | 5 | 15% |
| Researcher | 4 | 12% |
| Professor | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 3 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 13 | 38% |
| Agricultural and Biological Sciences | 12 | 35% |
| Neuroscience | 2 | 6% |
| Medicine and Dentistry | 2 | 6% |
| Immunology and Microbiology | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 3 | 9% |