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Mendeley readers
| Title |
Orthologs of the small RPB8 subunit of the eukaryotic RNA polymerases are conserved in hyperthermophilic Crenarchaeota and "Korarchaeota"
|
|---|---|
| Published in |
Biology Direct, December 2007
|
| DOI | 10.1186/1745-6150-2-38 |
| Pubmed ID | |
| Authors |
Eugene V Koonin, Kira S Makarova, James G Elkins |
| Abstract |
Although most of the key components of the transcription apparatus, and in particular, RNA polymerase (RNAP) subunits, are conserved between archaea and eukaryotes, no archaeal homologs of the small RPB8 subunit of eukaryotic RNAP have been detected. We report that orthologs of RPB8 are encoded in all sequenced genomes of hyperthermophilic Crenarchaeota and a recently sequenced "korarchaeal" genome, but not in Euryarchaeota or the mesophilic crenarchaeon Cenarchaeum symbiosum. These findings suggest that all 12 core subunits of eukaryotic RNAPs were already present in the last common ancestor of the extant archaea. |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 4% |
| United Kingdom | 1 | 2% |
| United States | 1 | 2% |
| Netherlands | 1 | 2% |
| Unknown | 42 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 21% |
| Researcher | 9 | 19% |
| Student > Master | 6 | 13% |
| Professor | 5 | 11% |
| Student > Bachelor | 4 | 9% |
| Other | 7 | 15% |
| Unknown | 6 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 26 | 55% |
| Biochemistry, Genetics and Molecular Biology | 10 | 21% |
| Immunology and Microbiology | 1 | 2% |
| Chemistry | 1 | 2% |
| Unknown | 9 | 19% |