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Strong association between pseudogenization mechanisms and gene sequence length

Overview of attention for article published in Biology Direct, October 2009
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Title
Strong association between pseudogenization mechanisms and gene sequence length
Published in
Biology Direct, October 2009
DOI 10.1186/1745-6150-4-38
Pubmed ID
Authors

Amit N Khachane, Paul M Harrison

Abstract

Pseudogenes arise from the decay of gene copies following either RNA-mediated duplication (processed pseudogenes) or DNA-mediated duplication (nonprocessed pseudogenes). Here, we show that long protein-coding genes tend to produce more nonprocessed pseudogenes than short genes, whereas the opposite is true for processed pseudogenes. Protein-coding genes longer than 3000 bp are 6 times more likely to produce nonprocessed pseudogenes than processed ones.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 9%
Korea, Republic of 1 5%
United States 1 5%
Unknown 18 82%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 27%
Researcher 6 27%
Student > Bachelor 2 9%
Professor > Associate Professor 2 9%
Student > Master 1 5%
Other 3 14%
Unknown 2 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 68%
Biochemistry, Genetics and Molecular Biology 3 14%
Mathematics 1 5%
Engineering 1 5%
Unknown 2 9%