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A (H1N1) pdm09 HA D222 variants associated with severity and mortality in patients during a second wave in Mexico

Overview of attention for article published in Virology Journal, January 2013
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Title
A (H1N1) pdm09 HA D222 variants associated with severity and mortality in patients during a second wave in Mexico
Published in
Virology Journal, January 2013
DOI 10.1186/1743-422x-10-41
Pubmed ID
Authors

Joel A Vazquez-Perez, Pavel Isa, Darwyn Kobasa, Christopher E Ormsby, Jose E Ramírez-Gonzalez, Damaris P Romero-Rodríguez, Charlene Ranadheera, Yan Li, Nathalie Bastien, Carissa Embury-Hyatt, Elizabeth González-Duran, Gisela Barrera-Badillo, Yuria Ablanedo-Terrazas, Edgar E Sevilla-Reyes, Marina Escalera-Zamudio, Ana G Cobián-Güemes, Irma Lopez, Joanna Ortiz-Alcántara, Celia Alpuche-Aranda, Jose R Perez-Padilla, Gustavo Reyes-Terán

Abstract

Pandemic type A (H1N1) influenza arose in early 2009, probably in Mexico and the United States, and reappeared in North America in September for seven more months. An amino acid substitution in the hemagglutinin (HA), D222G, has been reported in a significant proportion of patients with a severe and fatal outcome. We studied the prevalence of HA222 substitutions in patients in Mexico during the second wave and its association with clinical outcome and pathogenicity in a mouse model.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 22%
Student > Bachelor 8 16%
Student > Master 7 14%
Student > Ph. D. Student 5 10%
Other 3 6%
Other 7 14%
Unknown 10 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 25%
Medicine and Dentistry 9 18%
Biochemistry, Genetics and Molecular Biology 6 12%
Immunology and Microbiology 3 6%
Business, Management and Accounting 2 4%
Other 6 12%
Unknown 12 24%