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Mendeley readers
Attention Score in Context
| Title |
Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B
|
|---|---|
| Published in |
Journal of Translational Medicine, January 2014
|
| DOI | 10.1186/1479-5876-12-25 |
| Pubmed ID | |
| Authors |
Geoffrey L Rogers, Ashley T Martino, Irene Zolotukhin, Hildegund CJ Ertl, Roland W Herzog |
| Abstract |
Self-complementary adeno-associated virus (scAAV) vectors have become a desirable vector for therapeutic gene transfer due to their ability to produce greater levels of transgene than single-stranded AAV (ssAAV). However, recent reports have suggested that scAAV vectors are more immunogenic than ssAAV. In this study, we investigated the effects of a self-complementary genome during gene therapy with a therapeutic protein, human factor IX (hF.IX). |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 1% |
| Korea, Republic of | 1 | 1% |
| Unknown | 69 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 28% |
| Student > Bachelor | 14 | 20% |
| Researcher | 9 | 13% |
| Other | 4 | 6% |
| Student > Master | 4 | 6% |
| Other | 10 | 14% |
| Unknown | 10 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 26 | 37% |
| Agricultural and Biological Sciences | 17 | 24% |
| Medicine and Dentistry | 5 | 7% |
| Neuroscience | 3 | 4% |
| Psychology | 3 | 4% |
| Other | 7 | 10% |
| Unknown | 10 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 September 2019.
All research outputs
#3,774,158
of 22,741,406 outputs
Outputs from Journal of Translational Medicine
#614
of 3,975 outputs
Outputs of similar age
#45,952
of 306,469 outputs
Outputs of similar age from Journal of Translational Medicine
#22
of 122 outputs
Altmetric has tracked 22,741,406 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,975 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,469 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 122 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.