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Molecular features in arsenic-induced lung tumors

Overview of attention for article published in Molecular Cancer, March 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

blogs
1 blog

Citations

dimensions_citation
113 Dimensions

Readers on

mendeley
123 Mendeley
citeulike
1 CiteULike
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Title
Molecular features in arsenic-induced lung tumors
Published in
Molecular Cancer, March 2013
DOI 10.1186/1476-4598-12-20
Pubmed ID
Authors

Roland Hubaux, Daiana D Becker-Santos, Katey SS Enfield, David Rowbotham, Stephen Lam, Wan L Lam, Victor D Martinez

Abstract

Arsenic is a well-known human carcinogen, which potentially affects ~160 million people worldwide via exposure to unsafe levels in drinking water. Lungs are one of the main target organs for arsenic-related carcinogenesis. These tumors exhibit particular features, such as squamous cell-type specificity and high incidence among never smokers. Arsenic-induced malignant transformation is mainly related to the biotransformation process intended for the metabolic clearing of the carcinogen, which results in specific genetic and epigenetic alterations that ultimately affect key pathways in lung carcinogenesis. Based on this, lung tumors induced by arsenic exposure could be considered an additional subtype of lung cancer, especially in the case of never-smokers, where arsenic is a known etiological agent. In this article, we review the current knowledge on the various mechanisms of arsenic carcinogenicity and the specific roles of this metalloid in signaling pathways leading to lung cancer.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 123 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
India 1 <1%
Unknown 121 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 18%
Researcher 14 11%
Student > Master 13 11%
Student > Bachelor 13 11%
Student > Doctoral Student 6 5%
Other 18 15%
Unknown 37 30%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 25 20%
Agricultural and Biological Sciences 19 15%
Medicine and Dentistry 9 7%
Environmental Science 5 4%
Pharmacology, Toxicology and Pharmaceutical Science 5 4%
Other 16 13%
Unknown 44 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 November 2013.
All research outputs
#6,745,792
of 25,374,917 outputs
Outputs from Molecular Cancer
#537
of 1,918 outputs
Outputs of similar age
#53,695
of 210,228 outputs
Outputs of similar age from Molecular Cancer
#4
of 16 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,918 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,228 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.