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Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses

Overview of attention for article published in Retrovirology, November 2011
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#2 of 1,096)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
37 news outlets
blogs
4 blogs
patent
6 patents

Citations

dimensions_citation
290 Dimensions

Readers on

mendeley
289 Mendeley
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Title
Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses
Published in
Retrovirology, November 2011
DOI 10.1186/1742-4690-8-90
Pubmed ID
Authors

Ravi P Subramanian, Julia H Wildschutte, Crystal Russo, John M Coffin

Abstract

Integration of retroviral DNA into a germ cell may lead to a provirus that is transmitted vertically to that host's offspring as an endogenous retrovirus (ERV). In humans, ERVs (HERVs) comprise about 8% of the genome, the vast majority of which are truncated and/or highly mutated and no longer encode functional genes. The most recently active retroviruses that integrated into the human germ line are members of the Betaretrovirus-like HERV-K (HML-2) group, many of which contain intact open reading frames (ORFs) in some or all genes, sometimes encoding functional proteins that are expressed in various tissues. Interestingly, this expression is upregulated in many tumors ranging from breast and ovarian tissues to lymphomas and melanomas, as well as schizophrenia, rheumatoid arthritis, and other disorders.

Mendeley readers

The data shown below were compiled from readership statistics for 289 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
Germany 1 <1%
Canada 1 <1%
Brazil 1 <1%
Japan 1 <1%
Iran, Islamic Republic of 1 <1%
Unknown 281 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 68 24%
Researcher 48 17%
Student > Bachelor 40 14%
Student > Master 38 13%
Student > Doctoral Student 17 6%
Other 36 12%
Unknown 42 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 102 35%
Biochemistry, Genetics and Molecular Biology 73 25%
Medicine and Dentistry 24 8%
Immunology and Microbiology 19 7%
Computer Science 11 4%
Other 18 6%
Unknown 42 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 312. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 November 2022.
All research outputs
#86,912
of 22,458,746 outputs
Outputs from Retrovirology
#2
of 1,096 outputs
Outputs of similar age
#302
of 133,890 outputs
Outputs of similar age from Retrovirology
#1
of 56 outputs
Altmetric has tracked 22,458,746 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,096 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 133,890 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.