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IL-1β-induced activation of p38 promotes metastasis in gastric adenocarcinoma via upregulation of AP-1/c-fos, MMP2 and MMP9

Overview of attention for article published in Molecular Cancer, January 2014
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Title
IL-1β-induced activation of p38 promotes metastasis in gastric adenocarcinoma via upregulation of AP-1/c-fos, MMP2 and MMP9
Published in
Molecular Cancer, January 2014
DOI 10.1186/1476-4598-13-18
Pubmed ID
Authors

Qiaojia Huang, Fenghua Lan, Xiaoting Wang, Yinghao Yu, Xuenong Ouyang, Feng Zheng, Junyong Han, Youdong Lin, Yanchuan Xie, Feilai Xie, Wei Liu, Xiaoli Yang, Han Wang, Lihong Dong, Lie Wang, Jianming Tan

Abstract

Interleukin-1β (IL-1β) has been implicated in the progression of gastric adenocarcinoma (GA); however, the molecular mechanisms of action of IL-1β in GA are poorly characterized. P38 and JNK are the major MAPK family members that regulate IL-1β signaling pathways. Here, we investigated the role of both p38 and JNK in IL-1β-induced GA cell migration, invasion and metastatic potential.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 22%
Student > Bachelor 7 19%
Student > Master 6 16%
Student > Ph. D. Student 5 14%
Student > Doctoral Student 1 3%
Other 5 14%
Unknown 5 14%
Readers by discipline Count As %
Medicine and Dentistry 11 30%
Biochemistry, Genetics and Molecular Biology 10 27%
Agricultural and Biological Sciences 7 19%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Nursing and Health Professions 1 3%
Other 0 0%
Unknown 7 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2014.
All research outputs
#17,285,668
of 25,373,627 outputs
Outputs from Molecular Cancer
#1,230
of 1,919 outputs
Outputs of similar age
#203,250
of 322,361 outputs
Outputs of similar age from Molecular Cancer
#19
of 35 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,919 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,361 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.