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Potential for rapid antibody detection to identify tuberculous cattle with non-reactive tuberculin skin test results

Overview of attention for article published in BMC Veterinary Research, June 2017
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  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

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Citations

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Title
Potential for rapid antibody detection to identify tuberculous cattle with non-reactive tuberculin skin test results
Published in
BMC Veterinary Research, June 2017
DOI 10.1186/s12917-017-1085-5
Pubmed ID
Authors

W. Ray Waters, H. Martin Vordermeier, Shelley Rhodes, Bhagwati Khatri, Mitchell V. Palmer, Mayara F. Maggioli, Tyler C. Thacker, Jeffrey T. Nelson, Bruce V. Thomsen, Suelee Robbe-Austerman, Doris M. Bravo Garcia, Mark A. Schoenbaum, Mark S. Camacho, Jean S. Ray, Javan Esfandiari, Paul Lambotte, Rena Greenwald, Adrian Grandison, Alina Sikar-Gang, Konstantin P. Lyashchenko

Abstract

Bovine tuberculosis (TB) control programs generally rely on the tuberculin skin test (TST) for ante-mortem detection of Mycobacterium bovis-infected cattle. Present findings demonstrate that a rapid antibody test based on Dual-Path Platform (DPP(®)) technology, when applied 1-3 weeks after TST, detected 9 of 11 and 34 of 52 TST non-reactive yet M. bovis-infected cattle from the US and GB, respectively. The specificity of the assay ranged from 98.9% (n = 92, US) to 96.0% (n = 50, GB) with samples from TB-free herds. Multi-antigen print immunoassay (MAPIA) revealed the presence of antibodies to multiple antigens of M. bovis in sera from TST non-reactors diagnosed with TB. Thus, use of serologic assays in series with TST can identify a significant number of TST non-reactive tuberculous cattle for more efficient removal from TB-affected herds.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 41 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 17%
Student > Master 6 14%
Student > Doctoral Student 4 10%
Student > Bachelor 4 10%
Student > Ph. D. Student 4 10%
Other 6 14%
Unknown 11 26%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 14 33%
Agricultural and Biological Sciences 5 12%
Immunology and Microbiology 4 10%
Social Sciences 2 5%
Biochemistry, Genetics and Molecular Biology 1 2%
Other 4 10%
Unknown 12 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2017.
All research outputs
#13,481,383
of 22,979,862 outputs
Outputs from BMC Veterinary Research
#910
of 3,062 outputs
Outputs of similar age
#160,143
of 317,348 outputs
Outputs of similar age from BMC Veterinary Research
#38
of 89 outputs
Altmetric has tracked 22,979,862 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,062 research outputs from this source. They receive a mean Attention Score of 3.9. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,348 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.