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Measurement of Creatine kinase and Aspartate aminotransferase in saliva of dogs: a pilot study

Overview of attention for article published in BMC Veterinary Research, June 2017
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Mentioned by

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3 tweeters

Citations

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26 Dimensions

Readers on

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30 Mendeley
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Title
Measurement of Creatine kinase and Aspartate aminotransferase in saliva of dogs: a pilot study
Published in
BMC Veterinary Research, June 2017
DOI 10.1186/s12917-017-1080-x
Pubmed ID
Authors

Asta Tvarijonaviciute, Tomas Barranco, Monica Rubio, Jose Maria Carrillo, Silvia Martinez-Subiela, Fernando Tecles, Juana Dolores Carrillo, José J. Cerón

Abstract

Muscle enzymes in saliva have been reported to be possible markers of heart and muscle damage in humans. The aim of this study was to assess if Creatine kinase (CK) and Aspartate aminotransferase (AST) activities could be measured in canine saliva, and to evaluate their possible changes in situations of muscle damage. The spectrophotometric assays for CK and AST measurement in saliva of dogs showed intra- and inter-assay imprecision lower than 1 and 16% and coefficients of correlation close to 1 in linearity under dilution tests. Healthy dogs showed activities in saliva of CK between 27 and 121 U/L and AST between 46 and 144 U/L, whereas in saliva of dogs with muscle damage CK ranged between 132 and 3862 U/L and AST between 154 and 4340 U/L. Positive moderate correlations were found between saliva and serum activities of the two enzymes (CK, r = 0.579; P = 0.001; AST, r = 0.674; P = 0.001). CK and AST activities can be measured in canine saliva with commercially available spectrophotometric assays. In addition these enzymes show higher values in saliva of dogs with muscle damage and their values are moderately correlated with those of serum.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 5 17%
Student > Bachelor 4 13%
Researcher 4 13%
Student > Postgraduate 2 7%
Student > Ph. D. Student 2 7%
Other 3 10%
Unknown 10 33%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 13 43%
Medicine and Dentistry 3 10%
Agricultural and Biological Sciences 2 7%
Biochemistry, Genetics and Molecular Biology 1 3%
Nursing and Health Professions 1 3%
Other 0 0%
Unknown 10 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2017.
All research outputs
#14,350,775
of 22,979,862 outputs
Outputs from BMC Veterinary Research
#1,111
of 3,062 outputs
Outputs of similar age
#176,933
of 317,132 outputs
Outputs of similar age from BMC Veterinary Research
#52
of 89 outputs
Altmetric has tracked 22,979,862 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,062 research outputs from this source. They receive a mean Attention Score of 3.9. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,132 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.