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Mendeley readers
Attention Score in Context
| Title |
HIV Nef and Vpu protect HIV-infected CD4+ T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2
|
|---|---|
| Published in |
Retrovirology, February 2014
|
| DOI | 10.1186/1742-4690-11-15 |
| Pubmed ID | |
| Authors |
Tram NQ Pham, Sabelo Lukhele, Fadi Hajjar, Jean-Pierre Routy, Éric A Cohen |
| Abstract |
HIV proteins Nef and Vpu down-modulate various host factors to evade immune defenses. Indeed, the CD4 receptor is down-regulated by Nef and Vpu, whereas virion-tethering BST2 is depleted by Vpu. Antibody-dependent cell-mediated cytotoxicity (ADCC) is increasingly recognized as a potentially powerful anti-HIV response. Given that epitopes which are specific for ADCC-competent anti-HIV antibodies are transitionally exposed upon CD4-mediated HIV entry, we investigated whether by depleting CD4 and BST2, HIV could negatively affect ADCC function. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| Israel | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 67 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 27% |
| Researcher | 11 | 16% |
| Student > Master | 11 | 16% |
| Student > Bachelor | 7 | 10% |
| Professor | 4 | 6% |
| Other | 6 | 9% |
| Unknown | 12 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 19 | 27% |
| Agricultural and Biological Sciences | 19 | 27% |
| Biochemistry, Genetics and Molecular Biology | 8 | 11% |
| Medicine and Dentistry | 4 | 6% |
| Chemical Engineering | 2 | 3% |
| Other | 6 | 9% |
| Unknown | 12 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 July 2019.
All research outputs
#6,936,550
of 22,743,667 outputs
Outputs from Retrovirology
#369
of 1,105 outputs
Outputs of similar age
#83,670
of 307,252 outputs
Outputs of similar age from Retrovirology
#8
of 33 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 1,105 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,252 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.