Title |
Stage-specific differential gene expression profiling and functional network analysis during morphogenesis of diphyodont dentition in miniature pigs, Sus Scrofa
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Published in |
BMC Genomics, February 2014
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DOI | 10.1186/1471-2164-15-103 |
Pubmed ID | |
Authors |
Fu Wang, Jing Xiao, Wei Cong, Ang Li, Fulan Wei, Junji Xu, Chunmei Zhang, Zhipeng Fan, Junqi He, Songlin Wang |
Abstract |
Our current knowledge of tooth development derives mainly from studies in mice, which have only one set of non-replaced teeth, compared with the diphyodont dentition in humans. The miniature pig is also diphyodont, making it a valuable alternative model for understanding human tooth development and replacement. However, little is known about gene expression and function during swine odontogenesis. The goal of this study is to undertake the survey of differential gene expression profiling and functional network analysis during morphogenesis of diphyodont dentition in miniature pigs. The identification of genes related to diphyodont development should lead to a better understanding of morphogenetic patterns and the mechanisms of diphyodont replacement in large animal models and humans. |
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Unknown | 1 | 100% |
Demographic breakdown
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
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Unknown | 29 | 97% |
Demographic breakdown
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Researcher | 7 | 23% |
Student > Ph. D. Student | 5 | 17% |
Student > Bachelor | 4 | 13% |
Student > Doctoral Student | 3 | 10% |
Student > Master | 3 | 10% |
Other | 6 | 20% |
Unknown | 2 | 7% |
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Social Sciences | 1 | 3% |
Other | 3 | 10% |
Unknown | 4 | 13% |