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Portal hypertension as the initial manifestation of POEMS syndrome: a case report

Overview of attention for article published in BMC Hematology, May 2017
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Title
Portal hypertension as the initial manifestation of POEMS syndrome: a case report
Published in
BMC Hematology, May 2017
DOI 10.1186/s12878-017-0078-8
Pubmed ID
Authors

Lina Wu, Yue Li, Fang Yao, Chongmei Lu, Jian Li, Weixun Zhou, Jiaming Qian

Abstract

Portal hypertension has a broad differential diagnosis. POEMS syndrome is an uncommon cause of it. POEMS syndrome is a rare disease involving multiple organs. In differential diagnosis of portal hypertension, POEMS syndrome should be considered especially when other symptoms such as numbness, organomegaly, endocrine alteration and skin changes also present, as it is highlighted by our case. We report a 46-year-old Chinese male, a teacher, presenting with portal hypertension. Electromyography revealed peripheral neuropathy. Immunofixation showed monoclonal immunoglobulin A lambda protein. The diagnosis of POEMS syndrome was established. After treatment of lenalidomide combined with dexamethasone over 2 years, the patient achieved a considerable improvement. This case highlights the manifestation of portal hypertension in POEMS syndrome. Lenalidomide with or without dexamethasone is effective for portal hypertension due to POEMS syndrome, though esophageal and gastric varices seems not reversible so easily.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Lecturer > Senior Lecturer 1 17%
Other 1 17%
Student > Doctoral Student 1 17%
Student > Master 1 17%
Researcher 1 17%
Other 0 0%
Unknown 1 17%
Readers by discipline Count As %
Medicine and Dentistry 2 33%
Arts and Humanities 1 17%
Social Sciences 1 17%
Nursing and Health Professions 1 17%
Unknown 1 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2017.
All research outputs
#20,427,593
of 22,979,862 outputs
Outputs from BMC Hematology
#66
of 82 outputs
Outputs of similar age
#270,645
of 310,863 outputs
Outputs of similar age from BMC Hematology
#3
of 4 outputs
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