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CX3CR1 deficiency suppresses activation and neurotoxicity of microglia/macrophage in experimental ischemic stroke

Overview of attention for article published in Journal of Neuroinflammation, February 2014
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Title
CX3CR1 deficiency suppresses activation and neurotoxicity of microglia/macrophage in experimental ischemic stroke
Published in
Journal of Neuroinflammation, February 2014
DOI 10.1186/1742-2094-11-26
Pubmed ID
Authors

Zhiwei Tang, Yan Gan, Qiang Liu, Jun-Xiang Yin, Qingwei Liu, Jiong Shi, Fu-Dong Shi

Abstract

Chemokine (C-X3-C motif) ligand 1 (CX3CL1)/ CX3C chemokine receptor 1 (CX3CR1) signaling is important in modulating the communication between neurons and resident microglia/migrated macrophages in the central nervous system (CNS). Although CX3CR1 deficiency is associated with an improved outcome following ischemic brain injury, the mechanism of this observation is largely unknown. The aim of this study was to investigate how CX3CR1 deficiency influences microglia/macrophage functions in the context of its protection following brain ischemia.

X Demographics

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 1%
Unknown 136 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 20%
Researcher 25 18%
Student > Master 19 14%
Student > Bachelor 13 9%
Student > Doctoral Student 9 7%
Other 26 19%
Unknown 19 14%
Readers by discipline Count As %
Neuroscience 34 25%
Agricultural and Biological Sciences 29 21%
Medicine and Dentistry 25 18%
Biochemistry, Genetics and Molecular Biology 9 7%
Immunology and Microbiology 6 4%
Other 12 9%
Unknown 23 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2014.
All research outputs
#17,712,213
of 22,743,667 outputs
Outputs from Journal of Neuroinflammation
#1,930
of 2,617 outputs
Outputs of similar age
#220,980
of 307,468 outputs
Outputs of similar age from Journal of Neuroinflammation
#41
of 61 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,617 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,468 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.